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This mechanism is well-documented: a peer-reviewed review in Drugs evaluating Sermorelins use in the diagnosis and treatment of growth hormone deficiency confirms it works by stimulating endogenous pituitary GH release through the GHRH receptor

Cascinu S, Cordella L, ferro E et al

That factor turned out to be GHK-Cu

The protective association was strongest among women with low alcohol intake and faded toward no effect at around 16 grams per day (roughly one beer or glass of wine)

It's prescribed for patients with confirmed vitamin B12 deficiency, especially those who cannot absorb B12 properly from food or oral supplements