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The S2 classification reflects TB-500's structural connection to thymosin beta-4 and its documented growth factor activity
Damaged dopaminergic neurons release matrix metalloproteinase 3, -synuclein, and neuromelanin that superactivated microglia, inducing reactive microgliosis, enhancing of the neurotoxicity-related mediators, such ROS (Figure 3)
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It's unclear how a hydrophilic peptide would interact with an enzyme that processes steroid hormones
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