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Study Design and Population The EXPERT study was designed to compare outcomes before and after treatment switch (Fig

Interestingly, a specific GPX1 polymorphism resulting in a proline-to-leucine transition at position 198 (Pro198Leu) is associated with a reduction in GPx1 activity and found to be more prevalent in Keshan patients

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The extracted genomic DNA was then used as a template to amplify the desired fragments in each of the target genes using primers flanking the target sites