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A 2017 survey of the clinical practice patterns in the management of relapsing Graves disease

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In the presence of protein thiol groups, these quercetin-quinones will form toxic compounds that go on to exert pro-oxidant effects and cause damage throughout the body

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Because prolonged opening of the BBB is associated with neuronal network dysfunction and long-term BBB dysfunction itself also indicates cortical damage, it is presumed that BBB damage in the epileptic brain contributes to epilepsy comorbidities