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A 2025 Kinsey study showed that 18% of respondents said their sexual desire had increased on GLP-1s while 16% said it had decreased

This can lead to a significant reduction in calorie intake

People who already have slow gastric emptying (gastroparesis) need extra caution

In January of this year, the FDA noted that it had "received adverse event reports after patients used compounded semaglutide" and that "patients should not use a compounded drug if an approved drug is available to treat a patient." In July, the agency followed up with a notice that it had "received reports of adverse events, some requiring hospitalization, that may be related to overdoses due to dosing errors associated with compounded semaglutide injectable products." And in August, Eli Lilly, the maker of Zepbound and Mounjaro, sent a series of cease-and-desist letters to providers urging them to stop prescribing compounded versions of those drugs

For decades, Epithalon has been investigated in aging research due to its proposed influence on cellular senescence, telomere biology, DNA stability, and circadian regulation