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Improvement in symptoms can be seen within days to weeks of starting B12 supplementation

UK guidelines recommend monitoring clinical response and full blood count (typically at around 2 months) to ensure treatment adequacy, rather than routinely rechecking B12 levels after replacement has started

First 2472 Hours: Early Symptoms The initial 24 to 72 hours of treatment will bring about minor changes that you might start to observe

Their diet may not be as good for absorbing B12

For example, individuals with NAFLD exhibit increased intestinal permeability and prevalence of small intestine bacterial overgrowth, and these factors are associated with the severity of hepatic steatosis 19