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Biochemical studies of the GCL from plants revealed that these proteins are regulated by redox environment through a mechanism that differs from the heterodimeric enzymes (Jez et al., 2004
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Ferulic acid (FA), the main active component isolated from Angelica sinensis , has been documented to increase the levels of GSH and the expression of GPX in the myocardium by upregulating AMPK2 and activating Nrf2 signaling [41, 165]
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