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The clearest answer to date comes from a Phase 2 trial published in the New England Journal of Medicine in 2023, which reported 24.2% weight loss after 48 weeks at the highest dose in 338 adults with obesity but no other complications
In the obesity trial, maximal WL was achieved with retatrutide 12 mg after 48 weeks: -24.2% vs
All of this is to say: IM8s price point is a sore spot for the brand
GLP-1 therapies often cause faster weight loss with less lean mass preservation, leading to more pronounced and sudden skin laxity compared to gradual or surgically managed weight loss
Including these foods in your diet can provide a supplementary amount of creatine to support your muscle-building goals
