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Fat (adipose) tissue can release cytokines (cell-signaling molecules) such as tumor necrosis factor-alpha (TNF-) that interfere with the action of insulin (in this context, these cytokines are referred to as adipokines )
Trials that Aim to Answer the Big Questions Several research groups are pursuing multiyear studies designed to test whether metformin delays agerelated diseases such as cardiovascular events, cancer, and cognitive decline
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10.1002/jnr.23507 46 PorquetD.Andrs-BenitoP.Grin-FerrC.CaminsA.FerrerI.CanudasA
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