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Contraindications and Drug Interactions Absolute contraindications include Wilsons Disease or other copper metabolism disorders (risk of dangerous copper accumulation), known copper allergy or hypersensitivity (risk of severe allergic reactions), and pregnancy/breastfeeding (no safety data available for systemic use)

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Use a 31-gauge, 5/16-inch (8 mm) needle on a U-100 insulin syringe

Subcutaneous injection sites commonly include the abdomen (avoiding the navel area), outer thigh, or upper arm

503A compounding pharmacies operate under section 503A of the Federal Food, Drug, and Cosmetic Act