(12, 13) By improving glycemic control, enhancing insulin sensitivity, and reducing adiposity, GLP-1 therapies may decrease bone marrow adipose tissue (BMAT) formation and mitigate the harmful effects of hyperglycemia on bone quality
doi: 10.1038/jid.2010.192 38 GavalasNGAkhtarSGawkrodgerDJWatsonPFWeetmanAPKempEH
There are no controlled data in human pregnancy
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As a general guideline, Semaglutide GLP-1 injections are typically prescribed to individuals with a BMI of 30 or above or 27 and above with at least one weight-related condition, such as high cholesterol, osteoarthritis, or sleep apnea