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Hadley King is a board-certified dermatologist based in New York City
DPP-4 Inhibitors Mechanism of action Competitive inhibition of dipeptidyl-peptidase 4 slows degradation of endogenous incretins (GLP-1, GIP) Glucose-dependent insulin secretion Post-prandial glucagon release No direct effect on weight or insulin sensitivity Glycaemic efficacy Advantages Weight-neutral useful when metformin + SU cause weight concern Low hypoglycaemia risk (incretin-dependent action) Oral, generally once-daily
Key Takeaways GLP-1 drugs like Ozempic may cause dry mouth, gum inflammation, and dental complications
As with any medication, semaglutide may have side effects, including nausea, stomach pain, or fatigue
4.3.2.1.4 Bovine holo-beta-lactoglobulin Micronutritional supplementation with a holoBLG-based food for special medical purposes (FSMP) lozenge alleviates allergic symptoms in BALB/c mice, imitating the protective effect of farm living (vide infra) (115, 116)
