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Weight reduction most likely played a large role in heart health, but researchers are also finding convincing early evidence that GLP-1and the drugsmay reduce inflammation when bound to receptors
UCLA physicians have pointed out that the common risk of significant weight loss on GLP-1 drugs is being accompanied by sarcopenia, which can cause long-term negative health implications, such as increased fracture risk, decreased mobility, lowered metabolism, and reduced quality of life
Allen J et al
Individual factors including body composition, skin sensitivity, and psychological state also matter
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