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Patients should be counseled to report severe abdominal pain (potential pancreatitis), right upper quadrant pain (possible gallbladder disease), visual changes (especially with diabetic retinopathy), persistent nausea or vomiting, or signs of dehydration which may increase risk of acute kidney injury

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Injection Site Reactions: Itchiness, redness, or pain at the injection site (for injectable medications)

Consistent with this, the number of islets containing centrally located cells was proportionally increased in cell GLP-1RKO mice compared with that in WT mice (Figure 1, F and G

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