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Description

Mechanism of Action : Semaglutide is a GLP-1 receptor agonist

The comparator was dulaglutide rather than placebo, so this shows that tirzepatide is better than dulaglutide for kidneys, not that dulaglutide is bad

The analysis predicted that GLP-1 drugs could prevent thousands of cases of diabetes and cardiovascular disease and add months of high-quality life to patient lifetimes on average

doi:10.1007/s00125-016-4186-y 39

Meghan MD warn that without a robust maintenance planincluding lifestyle changes and potentially tapering strategiesthe metabolic benefits may be transient