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The ratio [GSH]/[GSSG] is thought to be around 100 for cells that are not under oxidative stress [41], and [GSH]/[GSSG] = 107.5 in our model cell
We show that the model reproduces precisely the empirically observed decline in liver GSH during starvation, as well as its diurnal variation under normal fed conditions
The starting dosage of Saxenda is 0.6 milligrams
This step is crucial for identifying potential stability issues, verifying target delivery capabilities, and confirming reproducibility
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