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In this situation, HSP70 blocks the activation of the inflammatory transcription factor NF-B and suppresses its cytokine-mediated translocation to the nucleus ( in vitro and in vivo models of ischemia, HSP70 inhibits the production of pro-inflammatory cytokines (TNF- and IL-6), inhibits the activity of matrix metalloprotein kinases (MMPs) and iNOS (Wang et al., 2012)
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Cadmium mutagenicity and human nucleotide excision repair protein XPA: CD, EXAFS and (1)H/(15)N-NMR spectroscopic studies on the zinc(II)- and cadmium(II)-associated minimal DNA-binding domain (M98-F219)
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