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25 Patients diagnosed with vitamin B 12 deficiency whose history and physical examination do not suggest an obvious dietary or malabsorptive etiology should be tested for pernicious anemia with anti-intrinsic factor antibodies (positive predictive value = 95%), particularly if other autoimmune disorders are present

Injections bypass the digestive system entirely, delivering B12 directly into the bloodstream for fast absorption

with a follow-up of 4.3 years, no increased rate of disc degeneration was found on MRI if the vertebral endplates were intact

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