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Unlicensed compounded semaglutide, which has circulated widely online, is not approved for use in the UK and has been the subject of MHRA safety warnings
It is important for people taking semaglutide to be aware of the potential side effects and to seek medical attention if they experience any of them
Recent Phase 3 data showed average weight reduction exceeding 28% in some participant groups after extended treatment periods
The safety profiles of both drugs are well-established individually, and no major pharmacokinetic interactions have been identified that would contraindicate concurrent use
Whether the amounts included in compounded formulations are therapeutically significant is a separate question
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