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DPP-4 is expressed in human pancreatic beta cells and its direct inhibition improves beta cell function and survival in type 2 diabetes

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PMID: 183 JiFHFuXHLiGQHeQQiuXG

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This paradox may be partially explained by the cellular source: endothelial NOS (eNOS)-derived NO appears protective, while inducible NOS (iNOS) from macrophages tends to promote fibrosis [83]

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