Although the appetite-suppressing effect of semaglutide leads to weight loss, it can also cause insufficient calorie intake, which favours muscle weakness, muscle breakdown and a reduction in resilience," says sports physician Prettin, which is in line with current scientific findings, such as those of a study from 2024, which found that muscle loss caused by the GLP-1 receptor agonist was 0.8 per cent higher than that caused by the natural ageing process
Common side effects According to the drug manufacturer, common side effects of liraglutide include: Nausea Vomiting Diarrhea Constipation Headache Injection site reactions Indigestion The reason digestion-related side effects are so common is because liraglutide (and all GLP-1s) interact with receptors in your stomach and intestines to slow your stomach emptying and trigger fullness, says Chichak
Other than GI-related side effects, patients on semaglutide also report serious side effects, such as kidney problems, pancreatitis, gallbladder disease, hypoglycemia (low blood sugar), and severe allergic reactions
After reconstitution, refrigeration is required
This widespread distribution explains the extensive brain protection these medications offer