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Upregulation of angiotensin II can activate NADPH oxidase enzyme complex in vascular smooth muscle cells and cardiomyocytes, further increasing the generation of ROS and participating in the progression of HF (Doughan et al., 2008)

However, no significant association was found between TMAO level and mortality in peritoneal dialysis patients

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Vitamin B12 appears in the milk of nursing mothers in concentrations that approximate the mother's vitamin B12 blood level