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Some people who experienced nausea or constipation while on Semaglutide find those symptoms ease once the drug clears their system, while others notice a temporary period of looser stools or stomach discomfort as digestion speeds back up

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(5) Kopchick JJ, Berryman DE, Puri V, Lee KY, Jorgensen JOL

No specific dose adjustment is required for renal impairment based on FDA labeling

B.LEADER Publication Committee on behalf of the LEADER Trial Investigators (2019)