Semaglutide, GLP-1 Drugs, and IBS: Managing Side Effects and Gut Health Aleks Jagiello BSc, MSc, RD Sep 11, 2025 17 min read Glucagon-like peptide-1 (GLP-1) receptor agonist medications, such as semaglutide (brand names Wegovy, Ozempic ), have surged in popularity for weight loss and type 2 diabetes management
The dual action of Mounjaro on both GIP and GLP-1 receptors may contribute to its potential for greater weight loss compared to Ozempic
Consider looking for online support groups or friends or coworkers who you know either have considered using GLP-1 drugs or are currently using or have used GLP-1 drugs for weight loss
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Dulaglutide (Trulicity) Strengths: Once-weekly dosing Easy-to-use auto-injector device Proven cardiovascular benefit Good tolerability profile Considerations: Less weight loss than semaglutide Moderate (not maximum) glucose efficacy Best for: Patients prioritizing convenience and tolerability over maximum efficacy