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Moreover, preclinical toxicity studies and the results of our Phase 1/2a clinical trials with GB-102 have not detected the presence of sunitinib in the systemic blood circulation at any time point
However, two newly developed injectable drugs, semaglutide and tirzepatide, have demonstrated remarkable weight-loss effects in multinational randomized phase III trials
ACKNOWLEDGEMENTS This work was supported by a LG Life Sciences grant (to H.S.K.)
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Third, the distance between mechanism and readout determines tractability
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