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The Lancet , 399(10326), 2192-2203
Rapid dose escalation significantly increases the severity and duration of gastrointestinal side effects
Lyophilization is a sophisticated freeze-drying process where the peptide is frozen and then the surrounding pressure is reduced to allow the frozen water to sublimate directly from a solid to a gas
Nguyen, H
Therefore, clinicians should focus on individualized risk assessment, transparent counseling, and shared decision-making to guide appropriate therapy
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