297 , G861-868
Minimal appetite impact, sometimes even reduced hunger
SGLT2i use is associated with an increased risk of DKA and UTI, but confers several favourable outcomes, notably preservation of renal function, reduced risk of developing heart failure and CKD, and of hospitalisation, despite a higher prevalence of heart failure, hypertension, IHD and CKD at baseline
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(One small prospective study of early pregnancy GLP-1 users in a handful of European countries and Israel, published recently in BMJ Open , found no increase in major birth defects or pregnancy loss, when compared with control groups of pregnant women with diabetes and pregnant women who are obese