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Extracted from the bark of the cinchona tree, quinine was not only the first effective treatment for malaria 400 years ago, but remarkably remains a common and effective treatment to this day

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However, these medications are not FDA-approved, so buyer beware. The competing GLP-1 drug tirzepatide (Mounjaro, Zepbound) is similarly branded by a single company, Cutler continued

The evidence consistently demonstrates that semaglutide is generally well-tolerated, with side effects that are predominantly gastrointestinal, mild-to-moderate in severity, transient in duration, and manageable through evidence-based strategies

Wegovy is FDA-approved specifically for chronic weight management at a higher dose of 2.4 mg per week