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This months Patent Gazette features Dunads covalent PIKfyve inhibitors, Storm Therapeutics DHX9 inhibitors, and Monte Rosas CCNE1 molecular glue degraders for biomarker-defined cancers

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Cagrilintide 2.4 mg Population: BMI 30, no diabetes Key Results (32 Weeks): Mean Weight Loss: 15.1% with CagriSema (combination) 9.8% with semaglutide 2.4 mg alone 7.7% with cagrilintide 2.4 mg alone Synergy Demonstrated: Combination produced 54% more weight loss than semaglutide alone, 96% more than cagrilintide alone 15% Weight Loss: 53% (CagriSema) vs

(2025, November 13)

Nemlekar PM et al