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This gene encodes a glutathione S-transferase belonging to the alpha class
Polycyclic aromatic hydrocarbons (PAHs) found in cigarette smoke, for example, have been shown to decrease the activity of P450 enzymes, leading to a decrease in SAMe production and impaired DNA methylation
Pharmacokinetic modeling would guide protocol optimization
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10.1016/0003-9861(76)90253-8 Arch
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