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Robust anti-obesity and metabolic effects of a dual GLP-1/glucagon receptor peptide agonist in rodents and non-human primates

Intriguingly, Pcsk9 mRNA trended higher in Dpp4 / mice and was increased in Dpp4 Gut/ mice, whereas Pcsk9 / mice exhibited reduced postprandial TG, attributed to reduced lymphatic chylomicron secretion and enhanced hepatic clearance (33)

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However, there are many other reasons a female may be overweight other than simple lifestyle choices, such as PMOS, which primarily reduces fertility by disrupting ovulation, she further explained

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