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Amyloid Precursor Protein (APP) May act as a substrate and a recognition unit for CRL4CRBN and Stub1 E3 ligases facilitating ubiquitination of proteins involved in presynaptic functions and neurodegeneration
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Research involving reproductive-aged men demonstrated that urinary levels of phthalate monoesters and oxidative metabolites were significantly associated with increased sperm DNA damage, indicating direct genotoxic effects of these ubiquitous chemicals (66)
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