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Of these, 3,948 (47.91%) psychiatric AE cases were for exenatide, 1,152 (13.98%) for liraglutide, 12 (0.15%) for lixisenatide, 1,833 (22.25%) for dulaglutide, 1,033 (12.54%) for semaglutide, and 262 (3.18%) were for tirzepatide ( Figure 1 )
Semaglutide targets GLP-1 receptors, while Tirzepatide targets both GLP-1 and GIP receptors
The safety review is not the same for both
Arnold, K., Bordoli, L., Kopp, J
LKB1 loss links serine metabolism to DNA methylation, whereas METTL13-driven eEF1AK55 methylation promotes tumorigenesis [405]
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