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Aim for 4050 grams of carbohydrate per hour via liquids, consumed in smaller, more frequent sips (every 1012 minutes) rather than large gulps every 45 minutes

One meta-analysis compared the highest dose of tirzepatide (15 mg) to the highest dose of semaglutide (2 mg) and found that tirzepatide resulted in a greater weight loss at a 17.8% reduction in body weight versus 12.4% for semaglutide

[9] [10] Several factors may explain why some individuals experience fatigue whilst taking GLP-1 medications: Reduced caloric intake : The appetite-suppressing effects can lead to significantly lower food consumption, potentially resulting in inadequate energy intake, particularly if patients are not consuming balanced, nutrient-dense meals

GLP-1 (Glucagon-Like Peptide-1): This hormone signals the brain to reduce appetite and "food noise"

Conducting meta-analyses in R with the metaphor package