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Peptides often work by saturating receptors or triggering a systemic response, which is less dependent on the user's mass
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Pleiotropic effects of glucagon-like peptide-1 (GLP-1)-based therapies on vascular complications in diabetes
Risk Stratification & Contraindications Patient safety must guide the initiation of GLP-1 therapy, and therapy should be withheld if contraindications are present: Absolute Contraindications: Personal or family history of Medullary Thyroid Carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Cautionary History: Previous pancreatitis or gastroparesis 5
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