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2016;164(1):50-56 Meier C, Staub JJ, Roth CB, Guglielmetti M, Kunz M, Miserez AR, Drewe J, Huber P, Herzog R, Mller B

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Taking breaks, typically four weeks off after two to three months on, allows your system to normalize and potentially reduces any cumulative effects

In patients with significant beta-cell failureoften those who have had diabetes for many yearsthere may be insufficient insulin-secreting capacity remaining for GLP-1 agonists to stimulate effectively

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