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Najafian M, Jahromi MZ, Nowroznejhad J, et al
High-quality liposomal supplementation is a more reliable way to meaningfully raise cellular levels
(2023) Bunyavanich S et al
Systemic effects remain less certain because peptides are generally broken down during digestion, which reduces the amount that reaches circulation in active form
Our identification of VRK2-mediated SLC7A11 trafficking suggests a potential immune evasion mechanism, as SLC7A11-high tumors often display T cell exclusion phenotypes [37], warranting future investigation into whether VRK2 expression could predict therapeutic response to combined ferroptosis inducers and immune checkpoint inhibitors
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