Across several preclinical models, Epitalon demonstrated a reduction in chromosomal aberrations, i.e., those misalignments, breaks, and translocations that set the stage for malignant transformation
Elevating NAD+ while inhibiting its methylation loss through NNMT inhibition may enhance mitochondrial biogenesis and oxidative phosphorylation efficiency
These findings, although obtained from models of oxidative stress and mitochondrial dysfunction rather than in autism models, are highly relevant because they target biological mechanism that are also characteristic of ASD (Sachdeva et al., 2022)
A meta-analytic review of auditory event-related potential components as endophenotypes for schizophrenia: perspectives from first-degree relatives
In addition, we applied flow cytometry to demonstrate that RT can be used for high-throughput quantification of GSH levels in single cells