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Neutrophil extracellular traps (NETs) are comprised of modified neutrophilic chromatin that is expelled into the system to neutralize and prevent the dissemination of microbes, whilst concurrently alerting the immune system of the infection [25,26,27]

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The location of the SMHT1 gene (17p11.2) resides within the 3.7 Mb region of chromosome 17 that is deleted in Smith-Magenis syndrome, SMS, a disorder associated with behavioral problems, psychomotor impairment, growth delay, speech delay, brachycephaly, midface hypoplasia, and a hoarse voice

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