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Your healthcare provider may recommend changes if: Blood sugar remains uncontrolled Weight loss goals require adjustment Side effects become difficult to tolerate Some patients continue both medications, while others reduce the metformin dose or switch therapies based on clinical response

Importante : Los pacientes con retinopata diabtica preexistente deben ser monitoreados cuidadosamente, ya que la mejora rpida del control glucmico puede asociarse con un empeoramiento temporal de la retinopata

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Furthermore, oxidative stress has been suggested to be involved in the pathogenesis of HT (52)

But anecdotes arent evidence, and the legal and health risks are substantial