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GSH conjugation (followed by secretion from the cell) may be either spontaneous or catalyzed by one of several enzymes, including the GSH-transferases (GSTs), which have wide substrate diversity

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doi: 10.1016/j.cmet.2018.03.001 45 KayaniyilSLozano-OrtegaGBennettHAJohnssonKShaunikAGrandySet al

For instance, N-acetylcysteine (NAC), a precursor to GSH, has shown promise in increasing brain GSH levels and improving symptoms in first episode psychosis patients

Hyperlipidemic diet causes loss of olfactory sensory neurons, reduces olfactory discrimination, and disrupts odor-reversal learning