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Guidelines for older adults with diabetes mention that sodium-glucose cotransporter-2 (SGLT2) inhibitors and glucagon-like peptide-1 (GLP1) receptor agonists might have favourable effects on cognition [6] based on a network meta-analysis [7]

dietary uptake Carnitine shuttle system Acylcarnitines and their roles Carnitine and microbiota Carnitine as a food supplement Clinical applications of carnitine and its metabolites Rare diseases History & Evolution 1905: discovery | 1927: structure elucidation Discovered in meat extracts, carnitine takes its name from the latin carnis meaning meat or flesh

Dietary modification alone is insufficient for treating established deficiency but plays a supportive role in prevention

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ACs and free carnitine (FC) are the main forms of carnitine in human blood (Figure 2)