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SKU: 42484108593

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ApJ 791, L9

MSC treatment resulted in hepatocyte proliferation and neovascularization through hepatic growth mediators WNT2 and HGF secreted by LSEC in the VEGF-A/Flk1/Id1 signaling pathway [99, 101]

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The functional expansion of Nrf2 in proliferating cells directs the enhancement of anabolic metabolism, maintains redox homeostasis and further promotes the activation of PI3KAkt signaling, suggesting the presence of positive feedback between Nrf2 and the PI3KAkt pathway in proliferating cells (Figure 9)