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Vertebrate-specific glutaredoxin is essential for brain development
ROS and oxidatively modified macromolecules function as damage-associated molecular patterns (DAMPs), engaging pattern recognition receptors (PRRs) on microglia, including Toll-like receptors (TLRs) and NOD-like receptors (NLRs), to initiate inflammatory cascades ( Microglia, the resident immune cells of the CNS, are tightly regulated under physiological conditions to maintain neural homeostasis
Kumari, S., Panda, T.K
BPC157as Potential Agent Rescuing from Cancer Cachexia
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