the truth about semaglutide and other weight loss drugs etc have become a widely discussed medication and a hot "shortcut" for weight loss, but it is important to understand that it is not a “magic solution” for Here’s the truth most people

For example, women taking oral contraceptives should take them at least one hour before an exenatide injection to maintain their effectiveness

The most common reasons include: Gastrointestinal side effects such as nausea, vomiting and diarrhea which are the single most frequently documented reason for stopping in large health system datasets High out of pocket cost and lack of insurance coverage particularly in individuals without diabetes Medication unavailability or pharmacy supply shortages which peaked in 2023early 2024 Perceived completion of therapy once target weight is reached or weight loss plateaus Concerns about long term safety or treatment burden of injections Many cohorts show substantial discontinuation by 3 months, with further losses by 6-9 months

doi: PubMed PMID: 30227157

Implications for employers: Employers are already well aware that the use of GLP-1 medications for both diabetes and obesity has increased dramatically

Crucially, the researchers noted that participants had not yet reached a weight plateau when the study ended, suggesting the true long-term potential could be even higher