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Moreover, the majority of studies have been performed in heterologous or insulinoma cell lines, often at high ligand concentrations, and confirmation in primary beta cells and in vivo will ultimately be required to determine the physiological importance of these processes
Lassen, M
The GLP-1 medicines semaglutide and tirzepatide do not alter disease-related pathology, behaviour or cognitive function in 5XFAD and APP/PS1 mice
Avoid repeated freezethaw cycles to maintain peptide stability and integrity
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