Desperate for an affordable source of the new generation of potent anti-obesity drugs, some people have turned to a potentially dangerous technique: mixing their own semaglutide (Ozempic, Wegovy) or tirzepatide (Mounjaro) at home
Your doctor may recommend adjusting your dose, pausing titration, or trying an over-the-counter antidiarrheal medication like loperamide
GLP-1 briefly slows the rate food moves through the gut, which explains the most common side effects: bloating and constipation
Furthermore, the risk of hypoglycaemiaa major challenge when using insulinis reportedly lower with GLP-1RAs, given their glucose-dependent mechanism of modulating insulin release and glucagon suppression [25]
For many patients, semaglutide is intended as part of a longer-term strategy that may include nutrition, physical activity, and behavioral support