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ROS formed as a natural byproduct of the normal metabolism of oxygen have important roles in cell signaling and homeostasis

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doi: 10.1210/jcem.83.4.4744 136 MaccarioMVeldhuisJDBroglioFVitoLDArvatEDeghenghiRet al

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Development of insulin resistance in mice lacking PGC-1 in adipose tissues

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L-carnitine supplementation in such individuals may prevent or reduce high ammonia levels ( hyperammonemia ) and the severity of liver and brain damage, according to some clinical trials [27]

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The immune regulation in cancer by the amino acid metabolizing enzymes ARG and IDO

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