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After screening the titles and abstracts, 119 studies were eliminated as they were trial registrations and abstracts only

Timing often aligns with nighttime administration to match natural growth hormone rhythms

Acta Psychiatr Scand

Two key structural features distinguish it from other GHRPs: (1) incorporation of an -aminoisobutyric residue (Aib) at position 1 replacing the histidine of classical GHRPs, stabilising the -turn conformation required for receptor activation, (2) presence of a D-2-naphthyl-alanine (D-2-Nal) at position 3 replacing the D-isomer tryptophan, increasing GHS-R1a selectivity over related receptors