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its theoretical advantage (physiological sleep architecture modulation without sedation) has not been confirmed by adequately powered trials
A 2017 meta-analysis found that ALA supplementation led to an average weight loss of 1.27 kg (2.8 lbs) and a BMI reduction of 0.43 kg/m compared to placebo
Apopa PL, He X, Ma Q
This matters because research suggests the pulsatile pattern may be important for optimal physiological response
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